Ohkawa lab.

Publications

*…corresponding author
†…These authors contributed equally to this work.

2017

  • Ueda J*†, Harada A†, Urahama T, Machida S, Maehara K, Hada M, Makino Y, Nogami J, Horikoshi N, Osakabe A, Taguchi H, Tanaka H, Tachiwana H, Yao T, Yamada M, Iwamoto T, Isotani A, Ikawa M, Tachibana T,Okada Y, Kimura H, Ohkawa Y, Kurumizaka H, Yamagata K.
    Testis-Specific Histone Variant H3t Gene Is Essential for Entry into Spermatogenesis.
    Cell Rep. 2017 Jan 17;18(3):593-600.
  • Yokota K, Kobayakawa K, Saito T, Hara M, Kijima K, Ohkawa Y, Harada A, Okazaki K, Ishihara K, Yoshida S, Kudo A, Iwamoto Y, Okada S.
    Periostin Promotes Scar Formation through the Interaction between Pericytes and InfiltratingMonocytes/Macrophages after Spinal Cord Injury.
    Am J Pathol. 2017 Jan 9. pii: S0002-9440(16)30531-4.

2016

  • Miyabayashi K, Shima Y, Inoue M, Sato T, Baba T, Ohkawa Y, Suyama M, Morohashi KI.
    Alterations in Fetal Leydig Cell Gene Expression during Fetal and Adult Development.
    Sex Dev. 2016 Dec 14.
  • Nakayama A, Nakaoka H, Yamamoto K, Sakiyama M, Shaukat A, Toyoda Y,Okada Y, Kamatani Y, Nakamura T, Takada T , Inoue K, Yasujima T, Yuasa H, Shirahama Y, Nakashima H, Shimizu S, Higashino T, Kawamura Y, Ogata H, Kawaguchi M, Ohkawa Y, Danjoh I, Tokumasu A, Ooyama K, Ito T, Kondo T, Wakai K, Stiburkova B, Pavelka K, Stamp LK, Dalbeth N; Eurogout Consortium, Sakurai Y, Suzuki H, Hosoyamada M, Fujimori S, Yokoo T, Hosoya T, Inoue I, Takahashi A, Kubo M, Ooyama H, Shimizu T, Ichida K, Shinomiya N, Merriman TR, Matsuo H.
    GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include uratetransporter genes.
    Ann Rheum Dis. 2016 Nov 29. pii: annrheumdis-2016-209632.
  • Sawano S, Komiya Y, Ichitsubo R, Ohkawa Y, Nakamura M, Tatsumi R, Ikeuchi Y, Mizunoya W.
    A One-Step Immunostaining Method to Visualize Rodent Muscle Fiber Type within a Single Specimen.
    PLoS One. 2016 Nov 4;11(11):e0166080.
  • Kuniyoshi Y†, Maehara K†, Iwasaki T, Hayashi M, Semba Y, Fujita M, Sato Y, Kimura H, Harada A, Ohkawa Y*.
    Identification of Immunoglobulin Gene Sequences from a Small Read Number of mRNA-Seq Using Hybridomas.
    PLoS One. 2016 Oct 27;11(10):e0165473.
  • Katayama Y, Nishiyama M, Shoji H, Ohkawa Y, Kawamura A, Sato T, Suyama M, Takumi T, Miyakawa T, Nakayama KI.
    CHD8 haploinsufficiency results inautistic-like phenotypes in mice.
    Nature. 2016 Sep 7.
  • Iwamori N, Tominaga K, Sato T, Riehle K, Iwamori T, Ohkawa Y, Coarfa C, Ono E, Matzuk MM.
    MRG15 is required for pre-mRNA splicing and spermatogenesis.
    Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):E5408-15.
  • Torigata K, Daisuke O, Mukai S, Hatanaka A, Ohka F, Motooka D, Nakamura S,Ohkawa Y, Yabuta N, Kondo Y, Nojima H.
    LATS2 Positively Regulates Polycomb Repressive Complex 2.
    PLoS One. 2016 Jul 19;11(7):e0158562.
  • Yabe-Wada T*, Matsuba S, Takeda K, Sato T, Suyama M, Ohkawa Y, Takai T, Shi H, Philpott CC, Nakamura A*.
    TLR signals posttranscriptionally regulate the cytokine trafficking mediator sortilin.
    Sci Rep. 2016 May 25;6:26566.
  • Yokota K, Saito T, Kobayakawa K, Kubota K, Hara M, Murata M, Ohkawa Y, Iwamoto Y, *Okada S.
    The feasibility of in vivo imaging of infiltrating blood cells for predicting the functional prognosis after spinal cord injury.
    Sci Rep. 2016 May 9;6:25673.
  • Kaimori JY, Maehara K, Hayashi-Takanaka Y, Harada A, Fukuda M, Yamamoto S, Ichimaru N, Umehara T, Yokoyama S, Matsuda R, Ikura T, Nagao K, Obuse C, Nozaki N, Takahara S, Takao T, Ohkawa Y, Kimura H*, Isaka Y.
    Histone H4 lysine 20 acetylation is associated with gene repression in human cells.
    Sci Rep. 2016 Apr 11;6:24318.
  • Kobayashi W, Takaku M, Machida S, Tachiwana H, Maehara K, Ohkawa Y, Kurumizaka H*.
    Chromatin architecture may dictate the target site for DMC1, but not for RAD51, during homologous pairing.
    Sci Rep. 2016 Apr 7;6:24228.
  • Kujirai T, Horikoshi N, Sato K, Maehara K, Machida S, Osakabe A, Kimura H, Ohkawa Y, *Kurumizaka H.
    Structure and function of human histone H3.Y nucleosome.
    Nucleic Acids Res. 2016 Mar 25.
  • Hayashi M, Maehara K, Harada A, Semba Y, Kudo K, Takahashi H, Oki S, Meno C, Ichiyanagi K, Akashi K, Ohkawa Y*..
    Chd5 Regulates MuERV-L/MERVL Expression in Mouse Embryonic Stem Cells Via H3K27me3 Modification and Histone H3.1/H3.2.
    J Cell Biochem 2016 Mar;117(3):780-92.
  • Tanaka M, *Shiota M, Nakao T, Uemura R, Nishi S, Ohkawa Y, Matsumoto M, Yamaguchi M, Osada-Oka M, Inagaki A, Takahashi K, Nakayama KI, Gi M, Izumi Y, Miura K, Iwao H.
    Identification of low-abundance proteins in serum via the isolation of HSP72 complexes.
    J Proteomics. 2016 Mar 16;136:214-21. pii: S1874-3919(16)30010-0.
  • Urahama T, Harada A, Maehara K, Horikoshi N, Sato K, Sato Y, Shiraishi K, Sugino N, Osakabe A, Tachiwana H, Kagawa W, Kimura H, Ohkawa Y, *Kurumizaka H.
    Histone H3.5 forms an unstable nucleosome and accumulates around transcription start sites in human testis.
    Epigenetics&Chromatin. 2016 Jan 15;9:2.
  • Oka M*, Mura S, Yamada K, Sangel P, Hirata S, Maehara K, Kawakami K, Tachibana T, Ohkawa Y, Kimura H, Yoneda Y*.
    Chromatin-prebound Crm1 recruits Nup98-HoxA9 fusion to induce aberrant expression of Hox cluster genes.
    Elife. 2016 Jan 7;5. pii: e09540.
  • Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, *Morohashi KI.
    Isolation and characterization of fetal Leydig progenitor cells of male mice.
    Endocrinology. 2016 Mar;157(3):1222-33.
  • Maehara K, Ohkawa Y*.
    Exploration of nucleosome positioning patterns in transcription factor function.
    Sci Rep. 2016 Jan 21;6:19620.

    2015

  • Hatanaka Y, Inoue K, Oikawa M, Kamimura S, Ogonuki N, Kodama EN, Ohkawa Y, Tsukada Y, *Ogura A.
    Histone chaperone CAF-1 mediates repressive histone modifications to protect preimplantation mouse embryos from endogenous retrotransposons.
    Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):14641-6.
  • Osakabe A, Adachi F, Arimura Y, Maehara K, Ohkawa Y, *Kurumizaka H.
    Influence of DNA methylation on positioning and DNA flexibility of nucleosomes with pericentric satellite DNA.
    Open Biol. 2015 Oct 7;5(10).
  • Maehara K, Harada A, Sato Y, Matsumoto M,Nakayama K, Kimura H, * Ohkawa Y.
    Tissue-specific expression of histone H3 variants diversified after species separation.
    Epigenetics&Chromatin 2015 Sep 17;8:35.
  • Hayashi-Takanaka Y, Maehara K, Harada A, Umehara T, Yokoyama S, Obuse C, Ohkawa Y, Nozaki N, *Kimura H.
    Distribution of histone H4 modifications as revealed by a panel of specific monoclonal antibodies.
    Chromosome Res. 2015 Dec;23(4):753-66.
  • Shimaji K, Konishi T, Tanaka S, Yoshida H, Kato Y, Ohkawa Y, Sato T, Suyama M, Kimura H,*Yamaguchi M.
    Genomewide identification of target genes of histone methyltransferase dG9a during Drosophila embryogenesis.
    Genes Cells. 2015 Nov;20(11):902-14.
  • Yokota K, Kobayakawa K, Kubota K, Miyawaki A, Okano H, Ohkawa Y, Iwamoto Y, *Okada S.
    Engrafted Neural Stem/Progenitor Cells Promote Functional Recovery through Synapse Reorganization with Spared Host Neurons after Spinal Cord Injury.
    Sci Rep. 2015 Aug 11;5(2):264-77.
  • Nishimura T, Sato T, Yamamoto Y, Watakabe I, Ohkawa Y, Suyama M, Kobayashi S, *Tanaka M.
    foxl3 is a germ cell-intrinsic factor involved in sperm-egg fate decision in medaka.
    Science. 2015 Jul 17;349(6245):328-31.
  • Nasipakb B, Padilla-Benavides T, Green K, Leszyk J, Mao W, Konda S, Sif S, Shaffer S, Ohkawa Y, *Imbalzano AN.
    Opposing calcium-dependent signalling pathways control skeletal muscle differentiation by regulating a chromatin remodelling enzyme.
    Nat Commun. 2015 Jun 17;6:7441.
  • Maehara K, *Ohkawa Y.
    agplus: a rapid and flexible tool for aggregation plots.
    Bioinformatics 2015 Sep 15;31(18):3046-7.
  • Sugimoto N, Maehara K, Yoshida K, Yasukouchi S, Osano S, Watanabe S, Aizawa M, Yugawa T, Kiyono T, Kurumizaka H, Ohkawa Y, *Fujita M.
    Cdt1-binding protein GRWD1 is a novel histone-binding protein that facilitates MCM loading through its influence on chromatin architecture.
    Nucleic Acids Res. 2015 Jul 13;43(12):5898-911.
  • Ohnishi YH, Ohnishi YN, Nakamura T, Ohno M, Kennedy PJ, Ohkawa Y, Nishi A, Neve R, Tsuzuki T, *Nestler EJ.
    PSMC5, a 19S Proteasomal ATPase, Regulates Cocaine Action in the Nucleus Accumbens.
    PLoS One. 2015 May 11;10(5):e0126710.
  • Tomita S, Abdalla MO, Fujiwara S, Matsumori H, Maehara K, Ohkawa Y, Iwase H, *Saitoh N, *Nakao M.
    A cluster of noncoding RNAs activates the ESR1 locus during breast cancer adaptation.
    Nat Commun. 2015 Apr 29;6:6966.
  • Kawaguchi T, Tanigawa A, Naganuma T, Ohkawa Y, Souquere S, Pierron G, *Hirose T.
    SWI/SNF chromatin-remodeling complexes function in noncoding RNA-dependent assembly of nuclear bodies.
    Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):4304-9.
  • Harada A, Mallappa C, Okada S, Butler JT, Baker SP, Lawrence JB, *Ohkawa Y, *Imbalzano AN.
    Spatial re-organization of myogenic regulatory sequences temporally controls gene expression.
    Nucleic Acids Res. 2015 Feb 27;43(4):2008-21.
  • Takahashi H, Takigawa I, Watanabe M, Anwar D, Shibata M, Tomomori-Sato C, Sato S, Ranjan A, Seidel CW, Tsukiyama T, Mizushima W, Hayashi M, Ohkawa Y, Conaway JW, Conaway RC, *Hatakeyama S.
    MED26 regulates the transcription of snRNA genes through the recruitment of little elongation complex.
    Nat Commun. 2015 Jan 9;6:5941.
  • Harada A, Maehara K, Sato Y, Konno D, Tachibana T, Kimura H, *Ohkawa Y.
    Incorporation of histone H3.1 suppresses the lineage potential of skeletal muscle.
    Nucleic Acids Res. 2015 Jan 43(2):775-86.
  • Nakamura M, *Shibata K, Hatano S, Sato T, Ohkawa Y, Yamada H, Ikuta K, Yoshikai Y.
    A genome-wide analysis identifies a notch-RBP-Jκ-IL-7Rα axis that controls IL-17-producing γδ T cell homeostasis in mice.
    J Immunol. 2015 Jan 1;194(1):243-51.

2014

  • Matsumoto M, Baba A, Yokota T, Nishikawa H, Ohkawa Y, Kayama H, Kallies A, Nutt SL, Sakaguchi S, Takeda K, *Kurosaki T, *Baba Y.
    Interleukin-10-producing plasmablasts exert regulatory function in autoimmune inflammation.
    Immunity. 2014 Dec 18;41(6):1040-51.
  • *Oki S, Maehara K, Ohkawa Y, *Meno C.
    SraTailor: Graphical user interface software for processing and visualizing ChIP-seq data.
    Genes Cells.2014 Oct 17 ;19(12):919-26.
  • Kobayakawa K, Kumamaru H, Saiwai H, Kubota K, Ohkawa Y, Kishimoto J, Yokota K, Ideta R, Shiba K, Tozaki-Saitoh H, Inoue K, Iwamoto Y, *Okada S.
    Acute hyperglycemia impairs functional improvement after spinal cord injury in mice and humans.
    Sci Transl Med.2014 Oct 1;6(256):256ra137.
  • *Stasevich TJ, Hayashi-Takanaka Y, Sato Y, Maehara K, Ohkawa Y, Sakata-Sogawa K,Tokunaga M, Nagase T, Nozaki N, James G. McNally JG, *Kimura H
    Regulation of RNA polymerase II activation by histone acetylation in single living cells.
    Nature. 2014 Sep 11;516(7530):272-5.
  • Tanaka M, Yamaguchi M, *Shiota M, Kawamoto Y, Takahashi K, Inagaki A, Osada-Oka M, Harada A, Wanibuchi H, Izumi Y, Miura K, Iwao H, Ohkawa Y.
    Establishment of neutralizing rat monoclonal antibodies for fibroblast growth factor-2.
    Monoclon Antib Immunodiagn Immunother. 2014 Aug;33(4):261-9.
  • Tamura I, Ohkawa Y, Sato T, Suyama M, Jozaki K, Okada M, Lee L, Maekawa R, Asada H, Sato S, Yamagata Y, Tamura H, *Sugino N.
    Genome-wide analysis of histone modifications in human endometrial stromal cells.
    Mol Endocrinol. 2014 Jul 28(10):1656-69.
  • *Yokoyama A, Igarashi K, Sato T, Takagi K, Otsuka I M, Shishido Y, Baba T, Ito R, Kanno J, Ohkawa Y, Morohashi KI, Sugawara A.
    Identification of Myelin Transcription Factor 1 (MyT1) as a Subunit of the Neural Cell Type-specific Lysine-specific Demethylase 1 (LSD1) Complex.
    J Biol Chem. 2014 Jun 27;289(26):18152-18162.
  • Ueda J, Maehara K, Mashiko D, Ichinose T, Yao T, Hori M, Sato Y, Kimura K, Ohkawa Y, *Yamagata K.
    Heterochromatin dynamics during the differentiation process revealed by the DNA methylation reporter mouse, MethylRO.
    Stem Cell Reports. 2014 Jun 3;2(6):910-24.
  • Baba T, Otake H, Sato T, Miyabayashi K, Shishido Y, Wang CY, Shima Y, Kimura H, Yagi M, Ishihara Y, Hino S, Ogawa H, Nakao M, Yamazaki T, Kang D, Ohkawa Y, Suyama M, Chung BC, *Morohashi K.
    Glycolytic genes are targets of the nuclear receptor Ad4BP/SF-1.
    Nat Commun. 2014 Apr 14;5:3634.
  • Tanaka M, Mun S, Harada A, Ohkawa Y, Inagaki A, Sano S, Takahashi K, Izumi Y, Osada-Oka M, Wanibuchi H, Yamagata M, Yukimura T, Miura K, *Shiota M, Iwao H.
    Hsc70 contributes to cancer cell survival by preventing Rab1A degradation under stress conditions.
    PLoS One. 2014 May 6;9(5):e96785.
  • Harada A, Hayashi M, Kuniyoshi Y, Semba Y, Sugahara S, Tachibana T, *Ohkawa Y, Fujita M.
    Generation of a monoclonal antibody for INI1/hSNF5/BAF47.
    Monoclon Antib Immunodiagn Immunother. 2014 Feb;33(1):49-51.
  • 49. Harada A, Okazaki E, Okada S, Tachibana T, *Ohkawa Y.
    Production of a monoclonal antibody for C/EBPβ: the subnuclear localization of C/EBPβ in mouse L929 cells.
    Monoclon Antib Immunodiagn Immunother. 2014 Feb;33(1):34-7.
  • LeBlanc SE, Wu Q, Barutcu AR, Xiao H, Ohkawa Y, *Imbalzano AN.
    The PPARγ locus makes long-range chromatin interactions with selected tissue-specific gene loci during adipocyte differentiation in a protein kinase A dependent manner.
    PLoS One. 2014 Jan 20;9(1):e86140.

2013

  • Maehara K, Odawara J, Harada A, Yoshimi T, Nagao K, Obuse C, Akashi K, Tachibana T, Sakata T, *Ohkawa Y.
    A co-localization model of paired ChIP-seq data using a large ENCODE data set enables comparison of multiple samples.
    Nucleic Acids Res. 2013 Jan 7;41(1):54-62.
  • *Katahira J, Okuzaki D, Inoue H, Yoneda Y, Maehara K, Ohkawa Y.
    Human TREX component Thoc5 affects alternative polyadenylation site choice by recruiting mammalian cleavage factor I.
    Nucleic Acids Res. 2013 Aug 1;41(14):7060-7072.
  • Saiwai H, Kumamaru H, Ohkawa Y, Kubota K, Kobayakawa K, Yamada H, Yokomizo T, Iwamoto Y, *Okada S.
    Ly6C+ Ly6G- Myeloid-derived suppressor cells play a critical role in the resolution of acute inflammation and the subsequent tissue repair process after spinal cord injury.
    J Neurochem. 2013 Apr;125(1):74-88.
  • Kumamaru H, Saiwai H, Kubota K, Kobayakawa K, Yokota K, Ohkawa Y, Shiba K, Iwamoto Y, *Okada S.
    Therapeutic activities of engrafted neural stem/precursor cells are not dormant in the chronically injured spinal cord.
    Stem Cells. 2013 Aug;31(8):1535-47.
  • Kitajima K, Oki S, Ohkawa Y, Sumi T, *Meno C.
    Wnt signaling regulates left-right axis formation in the node of mouse embryos.
    Dev Biol. 2013 Aug 15;380(2):222-32.
  • Yoshimi T, Ohkawa Y, Azuma M, *Tachibana T.
    A panel of specific monoclonal antibodies directed against various phosphorylated histones H3.
    Monoclon Antib Immunodiagn Immunother. 2013 Apr;32(2):119-24.
  • Villacorte M, Suzuki K, Hirasawa A, Ohkawa Y, Suyama M, Maruyama T, Aoki D, Ogino Y, Miyagawa S, Terabayashi T, Tomooka Y, Nakagata N, *Yamada G.
    β-Catenin signaling regulates Foxa2 expression during endometrial hyperplasia formation.
    Oncogene. 2013 Jul 18;32(29):3477-82.

2012

  • Harada A, Okada S, Konno D, Odawara J, Yoshimi T, Yoshimura S, Kumamaru H, Saiwai H, Tsubota T, Kurumizaka H, Akashi K, Tachibana T, Imbalzano AN, *Ohkawa Y.
    Chd2 interacts with H3.3 to determine myogenic cell fate.
    EMBO J. 2012 Jun 29;31(13):2994-3007.
  • Ohmi Y, Ohkawa Y, Yamauchi Y, Tajima O, Furukawa K, *Furukawa K.
    Essential roles of gangliosides in the formation and maintenance of membrane microdomains in brain tissues.
    Neurochem Res. 2012 Jun;37(6):1185-91.
  • Kumamaru H, Ohkawa Y, Saiwai H, Yamada H, Kubota K, Kobayakawa K, Akashi K, Okano H, Iwamoto Y, *Okada S.
    Direct isolation and RNA-seq reveal environment-dependent properties of engrafted neural stem/progenitor cells.
    Nat Commun. 2012;3:1140.
  • Fujii Y, Shiota M, Ohkawa Y, Baba A, Wanibuchi H, Kinashi T, *Kurosaki T, *Baba Y.
    Surf4 modulates STIM1-dependent calcium entry.
    Biochem Biophys Res Commun. 2012 Jun 15;422(4):615-20.
  • Kubota K, Saiwai H, Kumamaru H, Maeda T, Ohkawa Y, Aratani Y, Nagano T, Iwamoto Y, *Okada S.
    Myeloperoxidase exacerbates secondary injury by generating highly reactive oxygen species and mediating neutrophil recruitment in experimental spinal cord injury.
    Spine. 2012 Jul 15;37(16):1363-9.
  • Ohkawa Y, Mallappa C, Vallaster CS, *Imbalzano AN.
    An improved restriction enzyme accessibility assay for analyzing changes in chromatin structure in samples of limited cell number.
    Methods Mol Biol. 2012;798:531-42.
  • Ohkawa Y, Mallappa C, Vallaster CS, *Imbalzano AN.
    Isolation of nuclei from skeletal muscle satellite cells and myofibers for use in chromatin immunoprecipitation assays.
    Methods Mol Biol. 2012;798:517-30.
  • Kumamaru H, Saiwai H, Ohkawa Y, Yamada H, Iwamoto Y, *Okada S.
    Age-related differences in cellular and molecular profiles of inflammatory responses after spinal cord injury.
    J Cell Physiol. 2012 Apr;227(4):1335-46.

2011

  • Xiao H, Leblanc SE, Wu Q, Konda S, Salma N, Marfella CG, Ohkawa Y, *Imbalzano AN.
    Chromatin accessibility and transcription factor binding at the PPARγ2 promoter during adipogenesis is protein kinase A-dependent.
    J Cell Physiol. 2011 Jan;226(1):86-93.
  • Odawara J, Harada A, Yoshimi T, Maehara K, Tachibana T, Okada S, Akashi K, *Ohkawa Y.
    The classification of mRNA expression levels by the phosphorylation state of RNAPII CTD based on a combined genome-wide approach.
    BMC Genomics. 2011 Oct 20;12:516.
  • Tanaka M, Shiota M, Okada S, Harada A, Odawara J, Mun S, Iwao H, *Ohkawa Y.
    Generation of a rat monoclonal antibody specific for hsp72.
    Hybridoma. 2011 Aug;30(4):397-400.
  • *Okada S, Saiwai H, Kumamaru H, Kubota K, Harada A, Yamaguchi M, Iwamoto Y, *Ohkawa Y. Flow cytometric sorting of neuronal and glial nuclei from central nervous system tissue. J Cell Physiol. 2011 Feb;226(2):552-8.

2010

  • Okada S, Maeda T, Saiwai H, Ohkawa Y, Shiba K, Iwamoto Y.
    Ossification of the posterior longitudinal ligament of the lumbar spine: a case series.
    Neurosurgery. 2010 Nov;67(5):1311-8; discussion 1318.
  • Shiota M, Saiwai H, Mun S, Harada A, Okada S, Odawara J, Tanaka M, Iwao H, Ohkawa Y.
    Generation of a rat monoclonal antibody specific for heat shock cognate protein 70.
    Hybridoma 2010 Oct;29(5):453-6.
  • Kotani M, Harada A, Odawara J, Azuma M, Okada S, Nishiyama Y, Nakamura M, Tachibana T, Ohkawa Y.
    Monoclonal antibody specific for Dhx9/NDHII/RHA.
    Hybridoma 2010 Jun;29(3):259-61.
  • Harada A, Ohkawa Y, Ao S, Odawara J, Okada S, Azuma M, Nishiyama Y, Nakamura M, Tachibana T.
    Rat monoclonal antibody specific for MyoD.
    Hybridoma 2010 Jun;29(3):255-8.
  • Yoshimura S, Harada A, Odawara J, Azuma M, Okada S, Nakamura M, Ohkawa Y, Tachibana T.
    Rat monoclonal antibody specific for the chromatin remodeling factor, CHD1.
    Hybridoma 2010 Jun;29(3):237-40.
  • Saiwai H, Ohkawa Y, Yamada H, Kumamaru H, Harada A, Okano H, Yokomizo T, Iwamoto Y, Okada S.
    The LTB4-BLT1 axis mediates neutrophil infiltration and secondary injury in experimental spinal cord injury.
    Am J Pathol. 2010 May;176(5):2352-66.
  • Harada A, Yoshimura S, Odawara J, Azuma M, Okada S, Nakamura M, Tachibana T, Ohkawa Y.
    Generation of a rat monoclonal antibody specific for CHD2.
    Hybridoma 2010 Apr;29(2):173-7.
  • Harada A, Okada S, Odawara J, Kumamaru H, Saiwai H, Aoki M, Nakamura M, Nishiyama Y, Ohkawa Y.
    Production of a rat monoclonal antibody specific for Myf5.
    Hybridoma 2010 Feb;29(1):59-62.
  • Mallappa C, Nasipak BT, Etheridge L, Androphy EJ, Jones SN, Sagerström CG, Ohkawa Y, Imbalzano AN.
    Myogenic microRNA expression requires ATP-dependent chromatin remodeling enzyme function.
    Mol Cell Biol. 2010 Jul;30(13):3176-86.
  • Yoshimura S, Yoshimi T, Ohkawa Y, Azuma M, Tachibana T.
    A rat monoclonal antibody against the chromatin remodeling factor CHD5.
    Hybridoma 2010 Feb;29(1):63-6.

2009

  • Ohkawa Y, Harada A, Nakamura M, Yoshimura S, Tachibana T.
    Production of a rat monoclonal antibody against Brg1.
    Hybridoma 2009 Dec;28(6):463-6.
  • Okada S, Harada A, Saiwai H, Nakamura M, Ohkawa Y.
    Generation of a rat monoclonal antibody specific for Brm.
    Hybridoma 2009 Dec;28(6):455-8.
  • Harada A, Okada S, Saiwai H, Aoki M, Nakamura M, Ohkawa Y.
    Generation of a rat monoclonal antibody specific for Pax7.
    Hybridoma 2009 Dec;28(6):451-3.
  • Okada S, Maeda T, Ohkawa Y, Harimaya K, Saiwai H, Kumamaru H, Matsumoto Y, Doi T, Ueta T, Shiba K, Iwamoto Y.
    Does ossification of the posterior longitudinal ligament affect the neurological outcome after traumatic cervical cord injury?
    Spine. 2009 May 15;34(11):1148-52.

〜2008

  • Ohkawa Y, Yoshimura S, Higashi C, Marfella CG, Dacwag CS, Tachibana T, Imbalzano AN. Myogenin and the SWI/SNF ATPase Brg1 maintain myogenic gene expression at different stages of skeletal myogenesis.
    J Biol Chem. 2007 Mar 2;282(9):6564-70.
  • Dacwag CS, Ohkawa Y, Pal S, Sif S, Imbalzano AN.
    The protein arginine methyltransferase Prmt5 is required for myogenesis because it facilitates ATP-dependent chromatin remodeling.
    Mol Cell Biol. 2007 Jan;27(1):384-94.
  • Marfella CG1, Ohkawa Y, Coles AH, Garlick DS, Jones SN, Imbalzano AN.
    Mutation of the SNF2 family member Chd2 affects mouse development and survival.
    J Cell Physiol. 2006 Oct;209(1):162-71.
  • de la Serna IL, Ohkawa Y, Higashi C, Dutta C, Osias J, Kommajosyula N, Tachibana T, Imbalzano AN.
    The microphthalmia-associated transcription factor requires SWI/SNF enzymes to activate melanocyte-specific genes.
    J Biol Chem. 2006 Jul 21;281(29):20233-41.
  • de la Serna IL, Ohkawa Y, Imbalzano AN.
    Chromatin remodelling in mammalian differentiation: lessons from ATP-dependent remodellers.
    Nat Rev Genet. 2006 Jun;7(6):461-73.
  • Ohkawa Y, Marfella CG, Imbalzano AN.
    Skeletal muscle specification by myogenin and Mef2D via the SWI/SNF ATPase Brg1.
    EMBO J. 2006 Feb 8;25(3):490-501.
  • de la Serna IL, Ohkawa Y, Berkes CA, Bergstrom DA, Dacwag CS, Tapscott SJ, Imbalzano AN.
    MyoD targets chromatin remodeling complexes to the myogenin locus prior to forming a stable DNA-bound complex.
    Mol Cell Biol. 2005 May;25(10):3997-4009.
  • Young DW, Pratap J, Javed A, Weiner B, Ohkawa Y, van Wijnen A, Montecino M, Stein GS, Stein JL, Imbalzano AN, Lian JB.
    SWI/SNF chromatin remodeling complex is obligatory for BMP2-induced, Runx2-dependent skeletal gene expression that controls osteoblast differentiation.
    J Cell Biochem. 2005 Mar 1;94(4):720-30.
  • Takahashi M, Hayashi K, Yoshida K, Ohkawa Y, Komurasaki T, Kitabatake A, Ogawa A, Nishida W, Yano M, Monden M, Sobue K.
    Epiregulin as a major autocrine/paracrine factor released from ERK- and p38MAPK-activated vascular smooth muscle cells.
    Circulation. 2003 Nov 18;108(20):2524-9.
  • Yoshida K, Nishida W, Hayashi K, Ohkawa Y, Ogawa A, Aoki J, Arai H, Sobue K.
    Vascular remodeling induced by naturally occurring unsaturated lysophosphatidic
    acid in vivo. Circulation. 2003 Oct 7;108(14):1746-52.
  • Ohkawa Y, Hayashi K, Sobue K.
    Calcineurin-mediated pathway involved in the differentiated phenotype of smooth
    muscle cells. Biochem Biophys Res Commun. 2003 Jan 31;301(1):78-83.
  • Nishida W, Nakamura M, Mori S, Takahashi M, Ohkawa Y, Tadokoro S, Yoshida K, Hiwada K, Hayashi K, Sobue K.
    A triad of serum response factor and the GATA and NK families governs the transcription of smooth and cardiac muscle genes.
    J Biol Chem. 2002 Mar 1;277(9):7308-17.